Boris Johnson announced the new restrictions on Saturday which are set to come into force on Thursday and last until December 2.
The lockdown which is set to see pubs, restaurants, gyms and non-essential shops closing will also stop members of the public from staying at their second homes.
Brits cannot leave their houses unless for a good reason, such as buying food and essentials, going to work or taking exercise.
Downing Street has said the PM will follow the rules like anyone else - meaning he will not visit his country home of Chequers where he stayed after being discharged from hospital following his coronavirus battle.
It comes after fears of a mass exodus from UK cities to the countryside like seen in Paris, France.
In guidance published by the Government, overnight stays and holidays away - including in the UK and abroad - will not be allowed under the new restrictions, Cornwall Live reports.
This includes people looking to stay in second homes, with the official advice stating that this can be only be done if "specific exceptions" apply.
"Overnight stays and holidays away from primary residences will not be allowed," the Government says.
"This includes holidays abroad and in the UK. It also means you cannot stay in a second home, if you own one, or staying with anyone you do not live with or are in a support bubble with.
"There are specific exceptions, for example if you need to stay away from home (including in a second home) for work purposes, but this means people cannot travel overseas or within the UK, unless for work, education or other legally permitted reasons."
Earlier this year, amid the first lockdown, Devon Live reported that a number of second homeowners have travelled from all over the country with their boats to visit the town, leaving residents 'extremely frightened.'