Kanye, 43, was reportedly being helped by the Republican party during his rally for president, but Trump deflected a question, which asked him if this was the case.
He instead gushed over the rapper's wife, Keeping Up With The Kardashians star Kim Kardashian.
Trump was asked whether party operatives were helping Kanye to get him on election ballot papers.
He did not answer the question directly, and proceeded to praise Kim Kardashian for her efforts on criminal justice reform, saying she has a "good heart".
A reporter asked Trump whether "at least two people connected to Kanye West's effort to get on the ballot have been connected to the Republican Party".
The journalist added that this "push" was coming amid Kim Kardashian saying Kanye is having issues with his mental health, in what she has described a "bipolar episode".
Trump denied having any knowledge of helping Kanye, but said: "I like him. He's always been very nice to me."
He was then asked if he was "aware of" or had "encouraged anyone in the party to help him get on the ballot, including in swing states".
Trump reiterated: "No, not at all. Other than I get along with him very well. I like him."
He praised Kim, saying: "I like his wife. His wife recommended certain people – as you know for, including Alice Johnson who’s a remarkable woman – but his wife recommended certain people to get out of prison.
"They were in prison for a long time, a long, long time. It should have never happened.
"I took what she said very strong…Kim Kardashian. And she’s got a good heart, very good heart. And I like Kanye very much."