Mesut Ozil could leave Arsenal in January after being left out of their Premier League squad.

The 32-year-old is the highest-paid player in club history on £350,000-a-week but has not played since March.

Talks have yet to bear fruit overpaying up his contract and Ozil, who had already been left out of Arsenal’s Europa League squad, will now explore his options.

MLS club DC United remain interested in the German World Cup winner, who has fallen out of favour under Mikel Arteta and is in the final year of his contract.

Greece defender Sokratis Papastathopoulos has also been left out of both squads after failing to seal a move to Napoli during the transfer window.

The midfielder is set to be sent into exile and left out of Mikel Arteta's Premier League side
The midfielder has been sent into exile and left out of Mikel Arteta's Premier League side

Arsenal currently have 19 non-homegrown players over the age of 21, two more than the Premier League limit, and that has resulted in the axe for both players.

Meanwhile, Arteta faces a defensive headache for the next six games with Rob Holding potentially set to miss all of them.

While Sokratis Papastathopoulos appears to have fallen out of favour with Mikel Arteta
Sokratis Papastathopoulos has fallen out of favour with Mikel Arteta

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The defender was replaced by David Luiz in the starting line-up for Saturday's 1-0 defeat to Manchester City, after suffering tightness in his hamstring during the warm-up.

Before that Holding had been almost ever-present in the Arsenal team, having started all but one of their previous games this season.

Arsenal will be without Rob Holding for a short period

Arteta is now sweating on the results of a scan on Holding's hamstring, with the Gunners fearing the centre-half could be out of action for three to four weeks.

The worry is he could now miss Arsenal's Europa League opener away to Rapid Vienna on Thursday, as well as Premier League clashes against Leicester, Manchester United and Aston Villa.