Liverpool right-back Trent Alexander-Arnold suffered what looked to be a calf injury during the 1-1 draw with Manchester City on Sunday.
The 22-year-old could now a doubt for the upcoming matches for England during the international break.
The Reds took the lead after just 18 minutes thanks to a penalty from Mohamed Salah, before Gabriel Jesus's strike pegged them back not long after.
Alexander-Arnold suffered the blow while sprinting back to chase Raheem Sterling around an hour into the tight contest.
The England international immediately called for medical attention, before limping off.
Alexander-Arnold was replaced by utility man James Milner off the bench.
But the man who could well replace Alexander-Arnold for England is City’s Kyle Walker.
However, he didn’t have a game to remember himself after giving away the penalty for Liverpool’s goal.
And Roy Keane laid into the 30-year-old on Sky Sports when explaining how Sadio Mane managed to win the spot kick at half time.
"Because he's up against an idiot,” blasted Keane, |Kyle Walker, people tell me he's playing well, I don't think so.
“He's 30, an international player, he's a car crash, keeps making these types of mistake, and rightly punished for it.
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However, co-pundit Micah Richards disagreed with Keane, insisting that Walker “gambled” by making the challenge, but insisting he is still one of the best right-backs in the world.
“He's been on form, I think Roy is taking it a bit overboard there, he's been one of City's best players, but he gambles there."