Actress Jodie Whittaker has reportedly quit BBC Doctor Who after three years playing the lead role.
The 38-year-old TV star made history as she became the first-ever female to play the iconic part in the sci-fi fantasy.
Although the BBC are yet to comment on the claims Jodie has left, fans of the show and bookies have begun predicting who they think will play the fourteenth time lord.
My Family and Death in Paradise star Kris Marshall has been installed as 3/1 favourite with Betfair to replace Jodie, amid rumours she's waving goodbye to the world of Daleks and Cybermen.
As Jodie was the first woman to play The Doctor, two joint second-favourites with Betfair are both women. Shameless actress Maxine Peake and Game of Thrones' Natalie Dormer are both at 8/1.
Betfair spokesperson Sam Rosbottom said: "Whoever replaces Jodie Whittaker will have a tough act to follow - the Huddersfield actress having won the hearts of Whovians across the world. But the betting suggests that in Kris Marshall at 3/1, someone who has been linked with the famous role for years before Whittaker was handed the part, there is a favoured choice to get the top job.
"The likes of Tom Rosenthal and James Norton have been spoken about before as well - but if the producers decide to stick with a female doctor, Maxine Peake and Natalie Dormer as joint 8/1 second-favourites could be shrewd picks to make the Tardis their home for the foreseeable future."
Meanwhile, I May Destroy You star Michaela Coel is the early favourite with Ladbrokes to replace Jodie in the Tardis with her odds to take over at 5/1.
Jessica O'Reilly of Ladbrokes said: "Jodie Whittaker's shock exit from the Tardis means the betting is wide open, and it's currently Michaela Coel who punters would love to see become the next Doctor."
Fans will have to wait and see who Jodie Whittaker his handing over her Doctor Who sonic screwdriver to.