Viewers branded the interview a "car crash" and said it was "painful" to watch as Ivana shared her views on the president and his current wife Melania.
Fans went into meltdown on Twitter as they heard Ivana support her former husband, as well as sharing her own abhorrent views.
She said: "He is pro everything I believe in. He is Republican and so am I. He's achieved so much, especially with immigration.
"I am immigrant, but they have to come to the country legally, they have to get a job, they have to pay taxes like the rest of Americans...
"A lot of people don't dress even American, they dress whatever they dress in.
"And they don't get a job and they steal and they rape the women. That's not our idea."
Jane Moore told Ivana: "What you've just said about migrants a lot of people would find quite offensive.
"You're a migrant yourself - are you not shutting the door behind you? Do you not understand some people just want a better life? How you describe them is quite inhumane."
Ivana replied: "It is inhumane but everybody has to pick themselves up.
"They have to go and apply for the visa properly then they come to America. They can come and cross the border properly."
One viewer said: "I cannot believe the utter trash that Ivana Trump is spouting on #loosewomen . Why give this woman airtime?!"
A second said: "Ivana Trump omg!! Her remarks on immigration absolutely disturbing."
While another wrote: "This interview is SO painful..."
A third added: "Good god somebody make it stop! Car crash tv."
"Watching Loose Women with my jaw on the floor. Absolute car crash," penned a fourth.
Later on in the interview, things turned more awkward as the Loose Women ladies asked Ivana about her ex husband's wife Melania Trump.
When asked if she had met Melania, there was a cringeworthy silence before Ivana responded: "I don't understand the question."
Another fan added: "I'm still cringing thinking about Ivana Trump on #LooseWomen. The whole Melania questions part of the interview, pretending she didn't understand what they were saying..."
Loose Women airs weekdays at 12.30pm on ITV.